Myanna Buring (Marina Litvinenko), Tom Brooke (Alexander Litvinenko), Reece Shearsmith (The President/Jon), Lloyd Hutchinson (Dimitri Kovtun/Kamishnikov/Radiologist/Yaltsin), Michael Shaeffer (Andrei Lugovoi/Dr Gent/Gorbachev), Peter Polycarpou (Boris Bereszovsky/Walter/Dr Gunner), Gavin Spokes (DI Hyatt/Man with Stick), Thomas Arnold (Emmerson/Sergei/Mario/Tim/Brezhnev), Amanda Hadingue (Professor Dombey/Lluba/Dr Bhatt/Photographer), Sarah Seggari (Cabin Crew/Australian Cleaner/Nurse Rezan/Youth 3/Nurse), Bea Svistunenko (Anatoly/Nurse Michena/Waitress/Lludmilla), Robyn Moore (Galina/Receptionist/Technician/Marie Curie/Onstage Swing), Marc Graham (DS Hoar/Nurse David/Youth 1/FSB Officer 1/Ruslan/Onstage Swing), Callum Coates (Martin/Dr Virchis/FSB Officer 2/Onstage Swing), Yasmine Holness-Dove (Natalia/FSB Officer 3/Youth 2/Waitress 2/Dr Dudhniwala/Onstage Swing)