Kelsey Grammer (Edward Bloom), Jamie Muscato (Story Edward), Matthew Seadon-Young (Will Bloom), Clare Burt (Sandra Bloom), Laura Baldwin (Story Sandra), Frances McNamee (Josephine Bloom), Dean Nolan (Karl), Forbes Masson (Amos Calloway), Forbes Masson (Don Price), Landi Oshinowo (The Witch), Landi Oshinowo (Jenny Hill), Tanisha Spring (Story Jenny), Jonathan Stewart (Dr. Bennett), Sophie Linder-Lee (Mermaid/Librarian), George Ure (Zacky Price), Gemma McMeel (Peggy/Girl with Cat), Colby Mulgrew (Boy)