Neil Patrick Harris (Bobby/Bobbie), Patti LuPone (Joanne), Martha Plimpton (Sarah), Stephen Colbert (Harry), Jill Paice (Susan), Craig Bierko (Peter), Jennifer Laura Thompson (Jenny), Jon Cryer (David), Christina Hendricks (April/Andy), Chryssie Whitehead (Kathy/Theo), Anika Noni Rose (Marta/PJ), Katie Finneran (Amy/Jamie), Aaron Lazar (Paul), Jim Walton (Larry)