Santino Fontana (Eliot Rosewater), Brynn O'Malley (Silvia Rosewater), Skylar Astin (Norman Moshari), James Earl Jones (Kilgore Trout), Derrick Baskin (Charley Warmergran & others), Jeff Blumenkrantz (Thurmond McAllister), Manik Choksi (Psychiatrist & others), Eddie Cooper (Jerome & others), Kevin Del Aguila (Noyes Finnerty/Mail Boy/Al/Writer No. 1/Fred Rosewater), Clark Johnson (Senator Rosewater), Rebecca Naomi Jones (Mary Moody, Blanche, & others), Kevin Ligon (Delbert Peach & others), Marla Louissaint (Marla/Usher/Wheelchair), Liz McCartney (Diana Moon Glampers & others), Bonnie Milligan (Bonnie/Applicant No. 3/Usher/Kid), Kate Wetherhead (Dawn Leonard, Caroline Rosewater, & others)