Javier Muñoz (alt Alexander Hamilton), Alysha Deslorieux (u/s Eliza Hamilton), Austin Smith (u/s Aaron Burr), Renée Elise Goldsberry (Angelica Schuyler), Christopher Jackson (George Washington), Daveed Diggs (Marquis de Lafayette/Thomas Jefferson), Okieriete Onaodowan (Hercules Mulligan/James Madison), Anthony Ramos (John Laurens/Philip Hamilton), Jasmine Cephas Jones (Peggy Schuyler/Maria Reynolds), Jonathan Groff (King George III), Sydney James Harcourt (James Reynolds/Philip Schuyler/Doctor) (also known as Sydney Harcourt), Thayne Jasperson (Samuel Seabury), Jon Rua (Charles Lee), Gerald Avery (s/w George Eacker), Carleigh Bettiol, David Guzman, Emmy Raver-Lampman, Kamille Upshaw, Karlo Puno Garcia, Shonica Gooden, Voltaire Wade-Greene