Jimmie "JJ" Jeter (alt Alexander Hamilton), Sandra Okuboyejo (u/s Eliza Hamilton), Akron Watson (Aaron Burr), Nikki Renée Daniels (Angelica Schuyler), Tamar Greene (George Washington), Paris Nix (Marquis de Lafayette/Thomas Jefferson), Ebrin R Stanley (Hercules Mulligan/James Madison), Jamaal Fields-Green (John Laurens/Philip Hamilton), Aubin Wise (Peggy Schuyler/Maria Reynolds), Andrew Call (King George III), Robert Ariza (James Reynolds/Philip Schuyler/Doctor), Mikey Winslow (Samuel Seabury), Dylan Hoffinger (Charles Lee), Remmie Bourgeois (George Eacker)