Lin-Manuel Miranda (Usnavi), Krysta Rodriguez (u/s Nina), Christopher Jackson (Benny), Karen Olivo (Vanessa), Olga Merediz (Abuela Claudia), Carlos Gomez (Kevin), Priscilla Lopez (Camila), Robin de Jesús (Sonny), Andréa Burns (Daniela), Janet Dacal (Carla), Seth Stewart (Grafitti Pete), Eliseo Roman (Piragua Guy)