Michele Lee (Mame Dennis), Christine Ebersole (Vera Charles), Allyce Beasley (Agnes Gooch), Ben Platt (Patrick Dennis, age 10), Ben Davis (Patrick Dennis, age 19-29), John Schneider (Beauregard), Michael Lee (Ito), Robert Picardo (Babcock), Alan Thicke (Mr. Upson), Edie McClurg (Mrs. Doris Upson)