Danielle Wade (s/b Cady Heron), Taylor Louderman (Regina George), Krystina Alabado (Gretchen Wieners), Kate Rockwell (Karen Smith), Barrett Wilbert Weed (Janis Sarkisian), Grey Henson (Damian Hubbard), Brendon Stimson (u/s Aaron Samuels), Cheech Manohar (Kevin Gnapoor), Devon Hadsell (u/s Mrs. Heron/Ms. Norbury/Mrs. George), Rick Younger (Principal Duvall), Iain Young (s/w Mr. Heron), Myles McHale (Coach Carr/Glen Coco/Math Moderator), Talya Groves (s/w Dawn Schweitzer), Collins Conley (Lizzie Therman/Caroline Krafft), Ben Cook (Tyler Kimble), DeMarius R Copes (Christian Wiggins), Kevin Csolak (Shane Oman), Riza Takahashi (Sophie Kawachi), Brittany Nicholas (s/w Caitlyn Caussin), Curtis Holland (Jason Weems), Nikhil Saboo (Marwan Jitla), Jonalyn Saxer (Taylor Wedell), Kamille Upshaw (Rachel Hamilton), Bria Jene Williams (Grace Akinola), Gianna Yanelli (Sonja Acquino)