Olivia Kaufmann (s/b Cady Heron), Reneé Rapp (Regina George), Krystina Alabado (Gretchen Wieners), Kate Rockwell (Karen Smith), Gianna Yanelli (u/s Janis Sarkisian), Grey Henson (Damian Hubbard), Curtis Holland (u/s Aaron Samuels), Cheech Manohar (Kevin Gnapoor), Catherine Brunell (Mrs. Heron/Ms. Norbury/Mrs. George), Rick Younger (Principal Duvall), Drew Redington (Mr. Heron), Teddy Toye (Coach Carr/Glen Coco/Math Moderator), Stephanie Lynn Bissonnette (Dawn Schweitzer), Collins Conley (Lizzie Therman/Caroline Krafft), Jake Swain (Tyler Kimble), Iain Young (s/w Christian Wiggins), Pascal Pastrana (Shane Oman), Riza Takahashi (Sophie Kawachi), Aaron Alcaraz (s/w Jason Weems), Daryl Tofa (Marwan Jitla), Becca Petersen (Taylor Wedell), Maria Briggs (s/w Sonja Acquino)