Erika Henningsen (Cady Heron), Reneé Rapp (Regina George), Krystina Alabado (Gretchen Wieners), Kate Rockwell (Karen Smith), Barrett Wilbert Weed (Janis Sarkisian), Grey Henson (Damian Hubbard), Cameron Dallas (t/r Aaron Samuels), Cheech Manohar (Kevin Gnapoor), Catherine Brunell (Mrs. Heron/Ms. Norbury/Mrs. George), Rick Younger (Principal Duvall), Collins Conley (Lizzie Therman/Caroline Krafft), Daryl Tofa (Marwan Jitla), Gianna Yanelli (Sonja Acquino)