Erika Henningsen (Cady Heron), Cailen Fu (s/b Regina George), Krystina Alabado (Gretchen Wieners), Kate Rockwell (Karen Smith), Barrett Wilbert Weed (Janis Sarkisian), Drew Redington (u/s Damian Hubbard), Kyle Selig (Aaron Samuels), Cheech Manohar (Kevin Gnapoor), Catherine Brunell (Mrs. Heron/Ms. Norbury/Mrs. George), Rick Younger (Principal Duvall), Aaron Alcaraz (u/s Mr. Heron), Teddy Toye (Coach Carr/Glen Coco/Math Moderator), Jake Swain (Tyler Kimble), Darius Barnes (Christian Wiggins), Pascal Pastrana (Shane Oman), Daryl Tofa (Marwan Jitla)