Erika Henningsen (Cady Heron), Reneé Rapp (Regina George), Krystina Alabado (Gretchen Wieners), Becca Petersen (u/s Karen Smith), Barrett Wilbert Weed (Janis Sarkisian), Iain Young (u/s Damian Hubbard), Kyle Selig (Aaron Samuels), Cheech Manohar (Kevin Gnapoor), Jennifer Simard (Mrs. Heron/Ms. Norbury/Mrs. George), Ezra Knight (t/r Principal Duvall), Jake Swain (Tyler Kimble), Daryl Tofa (Marwan Jitla)