Becca Petersen (u/s Cady Heron), Taylor Louderman (Regina George), Ashley Park (Gretchen Wieners), Jonalyn Saxer (u/s Karen Smith), Barrett Wilbert Weed (Janis Sarkisian), Grey Henson (Damian Hubbard), Kyle Selig (Aaron Samuels), Nikhil Saboo (u/s Kevin Gnapoor), Jennifer Simard (Mrs. Heron/Ms. Norbury/Mrs. George), Rick Younger (Principal Duvall), Brendon Stimson (Mr. Heron), Myles McHale (Coach Carr/Glen Coco/Math Moderator), Ben Cook (Tyler Kimble), Patrick Garr (s/w Marwan Jitla)