Erika Henningsen (Cady Heron), Reneé Rapp (Regina George), Devon Hadsell (u/s Gretchen Wieners), Kate Rockwell (Karen Smith), Barrett Wilbert Weed (Janis Sarkisian), Grey Henson (Damian Hubbard), Kyle Selig (Aaron Samuels), Cheech Manohar (Kevin Gnapoor), Jennifer Simard (Mrs. Heron/Ms. Norbury/Mrs. George), Bria Jene Williams (u/s Principal Duvall)