Erika Henningsen (Cady Heron), Reneé Rapp (Regina George), Krystina Alabado (Gretchen Wieners), Kate Rockwell (Karen Smith), Barrett Wilbert Weed (Janis Sarkisian), Iain Young (u/s Damian Hubbard), Kyle Selig (Aaron Samuels), Daryl Tofa (u/s Kevin Gnapoor), Jennifer Simard (Mrs. Heron/Ms. Norbury/Mrs. George), Rick Younger (Principal Duvall), Drew Redington (Mr. Heron), Teddy Toye (Coach Carr/Glen Coco/Math Moderator), Brittany Nicholas (s/w Lizzie Therman/Caroline Krafft), Tovi Wayne (s/w Marwan Jitla)