Erika Henningsen (Cady Heron), Reneé Rapp (Regina George), Krystina Alabado (Gretchen Wieners), Kate Rockwell (Karen Smith), Olivia Kaufmann (s/b Janis Sarkisian), Grey Henson (Damian Hubbard), Brendon Stimson (u/s Aaron Samuels), Cheech Manohar (Kevin Gnapoor), Jennifer Simard (Mrs. Heron/Ms. Norbury/Mrs. George), Rick Younger (Principal Duvall), Aaron Alcaraz (s/w Mr. Heron), Brittany Nicholas (s/w Caitlyn Caussin), Iain Young (s/w Jason Weems), Maria Briggs (s/w Taylor Wedell)