Danielle Wade (Cady Heron), English Bernhardt (s/b Regina George), Megan Masako Haley (Gretchen Wieners), Jonalyn Saxer (Karen Smith), Mary Kate Morrissey (Janis Sarkisian), Will Branner (u/s Damian Hubbard), David Wright Jr (u/s Aaron Samuels), Kabir Bery (Kevin Gnapoor), Gaelen Gilliland (Mrs. Heron/Ms. Norbury/Mrs. George), Lawrence Street (Principal Duvall), Samuel Gerber (Mr. Heron), Samuel Gerber (Coach Carr/Glen Coco/Math Moderator), Marcus Shane (Tyler Kimble)