Robert Lenzi (Jim Stewart), Warner Miller (Al Bell), Mary Jo Mecca (Estelle Axton), Anastacia McCleskey (Deanie Parker), Harrison White (Rufus Thomas), Ricky Fante (Otis Redding), Allison Semmes (Carla Thomas/Jean Knight), Jon Harrison Taylor (Johnnie Taylor/Wilson Pickett), Tasha Taylor Johnson (Mavis Staples/Mable John), Wayne W Pretlow (Pops Staples), Boise Holmes (Isaac Hayes), Trevon Davis (David Porter), David LaMarr (Booker T. Jones), Skye Scott (Steve Cropper), Scott Stangland (Donald "Duck" Dunn), Kyle Bary (Al Jackson Jr.), Kevin Carolan (Jerry Wexler)