Reeve Carney (Peter Parker/Spider-Man), Kristen Faith Oei (u/s Mary Jane Watson), TV Carpio (Arachne), Patrick Page (Norman Osborn/Green Goblin), Michael Mulheren (J. Jonah Jameson), Ken Marks (Uncle Ben/Buttons), Isabel Keating (Aunt May/Maxie/Mrs. Gribrock), Timothy Warmen (MJ's Father/Stokes), Laura Beth Wells (Emily Osborn/Marbles), Matt Caplan (Flash/Bud), Luther Creek (Travis/Kong), Collin Baja (Carnage)