Jason Gotay (alt Peter Parker/Spider-Man), Rebecca Faulkenberry (Mary Jane Watson), Christina DeCicco (Arachne), Robert Cuccioli (Norman Osborn/Green Goblin), Michael Mulheren (J. Jonah Jameson), Ken Marks (Uncle Ben/Buttons), Isabel Keating (Aunt May/Maxie/Mrs. Gribrock), Laura Beth Wells (Emily Osborn/Marbles), Jake Odmark (Flash/Bud)