Jake Epstein (alt Peter Parker/Spider-Man), Rebecca Faulkenberry (Mary Jane Watson), Christina DeCicco (Arachne), Robert Cuccioli (Norman Osborn/Green Goblin), Ken Marks (Uncle Ben/Buttons), Isabel Keating (Aunt May/Maxie/Mrs. Gribrock), Timothy Warmen (MJ's Father/Stokes), Emily Shoolin (Emily Osborn/Marbles), Jake Odmark (Flash/Bud), Dwayne Clark (Robertson/Boyle), Jamison Scott (u/s Travis/Kong)