Jake Gyllenhaal (Georges Seurat / George), Annaleigh Ashford (Dot / Marie), Penny Fuller (Old Lady), Jennifer Sanchez (Nurse), Robert Sean Leonard (Jules), Erin Davie (Yvonne), Claybourne Elder (Soldier), Ashley Park (Celeste #1), Jenni Barber (Celeste #2), Brooks Ashmanskas (Mr.), Liz McCartney (Mrs.), Ruthie Ann Miles (Frieda), Phillip Boykin (Boatman), Jordan Gelber (Louis), Mattea Conforti (Louise), Robert Sean Leonard (Bob Greenberg), Erin Davie (Naomi Eisen), Jenni Barber (Elaine), Liz McCartney (Harriet Pawling), Jordan Gelber (Billy Webster), Brooks Ashmanskas (Charles Redmond), Claybourne Elder (Alex), Ruthie Ann Miles (Betty), Phillip Boykin (Lee Randolph), Penny Fuller (Blair Daniels), Jennifer Sanchez (Samantha), Ashley Park (Theresa)