Eric Bogosian (Satan), Liza Colón-Zayas (Gloria/Mother Teresa/Ensemble), Jeffrey DeMunn (Judge Littlefield/Caiaphas the Elder/St. Matthew), Yetta Gottesman (Loretta/Mary Magdalene/Ensemble), Craig "muMs" Grant (Matthias of Galilee/Delayne/St. Peter/Soldier 2/Ensemble), Stephen McKinley Henderson (Pontius Pilate/Uncle Pino), Salvatore Inzerillo (Bailiff/Simon the Zealot/Ensemble), Adrian Martinez (Boaz the Assyrian Thief/Sigmund Freud/St. Thomas/Soldier 1), John Ortiz (Jesus of Nazareth), Sam Rockwell (Judas Iscariot), Elizabeth Rodriguez (Saint Monica/Soldier 3/Ensemble), Deborah Rush (Henrietta Iscariot/Sister Glenna/Ensemble), Kohl Sudduth (Butch Honeywell, Ensemble), Callie Thorne (Fabiana Aziza Cunningham), Yul Vázquez (Yusef El-Fayoumy)